Vesicular glutamate transporters in the lateral geniculate nucleus: expression of VGLUT2 by retinal terminals

Peter W Land; Elizabeth Kyonka; L Shamalla-Hannah

doi:10.1016/j.brainres.2003.10.032

Vesicular glutamate transporters in the lateral geniculate nucleus: expression of VGLUT2 by retinal terminals

Peter W Land
, Elizabeth Kyonka
, L Shamalla-Hannah

School of Psychology

Research output: Contribution to journal › Article › peer-review

53 Citations (Scopus)

Abstract

We used immunohistochemistry to localize vesicular glutamate transporters VGLUT1 and VGLUT2 in the rat lateral geniculate nucleus. The lateral geniculate nucleus is intensely immunoreactive for both transporters. Monocular eye removal abolished staining for VGLUT2 in a pattern corresponding to the distribution of terminals from the missing eye, without affecting distribution of VGLUT1 immunoreactivity. These data indicate retinal ganglion cells are the source of VGLUT2-containing synapses in the lateral geniculate nucleus.

Original language	English
Pages (from-to)	251-254
Journal	Brain Research
Volume	996
Issue number	2
DOIs	https://doi.org/10.1016/j.brainres.2003.10.032
Publication status	Published - 2004

Keywords

Sensory Systems
Central Nervous System
Biological Psychology (Neuropsychology, Psychopharmacology, Physiological Psychology)

Access to Document

10.1016/j.brainres.2003.10.032

https://hdl.handle.net/1959.11/22547

Handle.net

Persistent link

Cite this

@article{7579076259434283b1b01985573dad4e,

title = "Vesicular glutamate transporters in the lateral geniculate nucleus: expression of VGLUT2 by retinal terminals",

abstract = "We used immunohistochemistry to localize vesicular glutamate transporters VGLUT1 and VGLUT2 in the rat lateral geniculate nucleus. The lateral geniculate nucleus is intensely immunoreactive for both transporters. Monocular eye removal abolished staining for VGLUT2 in a pattern corresponding to the distribution of terminals from the missing eye, without affecting distribution of VGLUT1 immunoreactivity. These data indicate retinal ganglion cells are the source of VGLUT2-containing synapses in the lateral geniculate nucleus.",

keywords = "Sensory Systems, Central Nervous System, Biological Psychology (Neuropsychology, Psychopharmacology, Physiological Psychology)",

author = "Land, \{Peter W\} and Elizabeth Kyonka and L Shamalla-Hannah",

year = "2004",

doi = "10.1016/j.brainres.2003.10.032",

language = "English",

volume = "996",

pages = "251--254",

journal = "Brain Research",

issn = "0006-8993",

publisher = "Elsevier BV",

number = "2",

}

TY - JOUR

T1 - Vesicular glutamate transporters in the lateral geniculate nucleus

T2 - expression of VGLUT2 by retinal terminals

AU - Land, Peter W

AU - Kyonka, Elizabeth

AU - Shamalla-Hannah, L

PY - 2004

Y1 - 2004

N2 - We used immunohistochemistry to localize vesicular glutamate transporters VGLUT1 and VGLUT2 in the rat lateral geniculate nucleus. The lateral geniculate nucleus is intensely immunoreactive for both transporters. Monocular eye removal abolished staining for VGLUT2 in a pattern corresponding to the distribution of terminals from the missing eye, without affecting distribution of VGLUT1 immunoreactivity. These data indicate retinal ganglion cells are the source of VGLUT2-containing synapses in the lateral geniculate nucleus.

AB - We used immunohistochemistry to localize vesicular glutamate transporters VGLUT1 and VGLUT2 in the rat lateral geniculate nucleus. The lateral geniculate nucleus is intensely immunoreactive for both transporters. Monocular eye removal abolished staining for VGLUT2 in a pattern corresponding to the distribution of terminals from the missing eye, without affecting distribution of VGLUT1 immunoreactivity. These data indicate retinal ganglion cells are the source of VGLUT2-containing synapses in the lateral geniculate nucleus.

KW - Sensory Systems

KW - Central Nervous System

KW - Biological Psychology (Neuropsychology, Psychopharmacology, Physiological Psychology)

U2 - 10.1016/j.brainres.2003.10.032

DO - 10.1016/j.brainres.2003.10.032

M3 - Article

SN - 0006-8993

VL - 996

SP - 251

EP - 254

JO - Brain Research

JF - Brain Research

IS - 2

ER -

Vesicular glutamate transporters in the lateral geniculate nucleus: expression of VGLUT2 by retinal terminals

Abstract

Keywords

Access to Document

Handle.net

Fingerprint

Cite this