Variability in the Distributions of Single Nucleotide Polymorphism Effects in Livestock Populations

Erica Smith; John M Henshall

Variability in the Distributions of Single Nucleotide Polymorphism Effects in Livestock Populations

Erica Smith, John M Henshall

Chemistry

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

Abstract

Variability in the distributions of single nucleotide polymorphisms (SNP) effects were investigated by simulation. Realised distributions after thousands of generations of selection were found to be sensitive to parameters relating to the genome size, SNP density, population size and the distribution of sampled SNP effects. In particular, the distributions were not generally exponential, and in some cases SNPs of smaller effect were less likely to segregate than SNPs of larger effect.

Original language	English
Title of host publication	Proceedings of the Association for the Advancement of Animal Breeding and Genetics
Editors	Alex Safari, Bill Pattie, Barrie Restall
Place of Publication	Armidale, Australia
Publisher	Association for the Advancement of Animal Breeding and Genetics (AAABG)
Pages	65-67
Volume	18
ISBN (Print)	9780646521039
Publication status	Published - 2009
Event	AAABG 2009: 18th Conference of the Association for the Advancement of Animal Breeding and Genetics - Barossa Valley, Australia Duration: 27 Sept 2009 → 2 Oct 2009

Conference

Conference	AAABG 2009: 18th Conference of the Association for the Advancement of Animal Breeding and Genetics
City	Barossa Valley, Australia
Period	27/09/09 → 2/10/09

Keywords

Animal Breeding
Genomics
Quantitative Genetics (incl Disease and Trait Mapping Genetics)

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https://hdl.handle.net/1959.11/7862

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Smith, E., & Henshall, J. M. (2009). Variability in the Distributions of Single Nucleotide Polymorphism Effects in Livestock Populations. In A. Safari, B. Pattie, & B. Restall (Eds.), Proceedings of the Association for the Advancement of Animal Breeding and Genetics (Vol. 18, pp. 65-67). Association for the Advancement of Animal Breeding and Genetics (AAABG). https://hdl.handle.net/1959.11/7862

Smith, Erica ; Henshall, John M. / Variability in the Distributions of Single Nucleotide Polymorphism Effects in Livestock Populations. Proceedings of the Association for the Advancement of Animal Breeding and Genetics. editor / Alex Safari ; Bill Pattie ; Barrie Restall. Vol. 18 Armidale, Australia : Association for the Advancement of Animal Breeding and Genetics (AAABG), 2009. pp. 65-67

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title = "Variability in the Distributions of Single Nucleotide Polymorphism Effects in Livestock Populations",

abstract = "Variability in the distributions of single nucleotide polymorphisms (SNP) effects were investigated by simulation. Realised distributions after thousands of generations of selection were found to be sensitive to parameters relating to the genome size, SNP density, population size and the distribution of sampled SNP effects. In particular, the distributions were not generally exponential, and in some cases SNPs of smaller effect were less likely to segregate than SNPs of larger effect.",

keywords = "Animal Breeding, Genomics, Quantitative Genetics (incl Disease and Trait Mapping Genetics)",

author = "Erica Smith and Henshall, \{John M\}",

year = "2009",

language = "English",

isbn = "9780646521039",

volume = "18",

pages = "65--67",

editor = "Alex Safari and Bill Pattie and Barrie Restall",

booktitle = "Proceedings of the Association for the Advancement of Animal Breeding and Genetics",

publisher = "Association for the Advancement of Animal Breeding and Genetics (AAABG)",

note = "AAABG 2009: 18th Conference of the Association for the Advancement of Animal Breeding and Genetics ; Conference date: 27-09-2009 Through 02-10-2009",

}

Smith, E & Henshall, JM 2009, Variability in the Distributions of Single Nucleotide Polymorphism Effects in Livestock Populations. in A Safari, B Pattie & B Restall (eds), Proceedings of the Association for the Advancement of Animal Breeding and Genetics. vol. 18, Association for the Advancement of Animal Breeding and Genetics (AAABG), Armidale, Australia, pp. 65-67, AAABG 2009: 18th Conference of the Association for the Advancement of Animal Breeding and Genetics, Barossa Valley, Australia, 27/09/09. <https://hdl.handle.net/1959.11/7862>

Variability in the Distributions of Single Nucleotide Polymorphism Effects in Livestock Populations. / Smith, Erica; Henshall, John M.
Proceedings of the Association for the Advancement of Animal Breeding and Genetics. ed. / Alex Safari; Bill Pattie; Barrie Restall. Vol. 18 Armidale, Australia: Association for the Advancement of Animal Breeding and Genetics (AAABG), 2009. p. 65-67.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

TY - GEN

T1 - Variability in the Distributions of Single Nucleotide Polymorphism Effects in Livestock Populations

AU - Smith, Erica

AU - Henshall, John M

PY - 2009

Y1 - 2009

N2 - Variability in the distributions of single nucleotide polymorphisms (SNP) effects were investigated by simulation. Realised distributions after thousands of generations of selection were found to be sensitive to parameters relating to the genome size, SNP density, population size and the distribution of sampled SNP effects. In particular, the distributions were not generally exponential, and in some cases SNPs of smaller effect were less likely to segregate than SNPs of larger effect.

AB - Variability in the distributions of single nucleotide polymorphisms (SNP) effects were investigated by simulation. Realised distributions after thousands of generations of selection were found to be sensitive to parameters relating to the genome size, SNP density, population size and the distribution of sampled SNP effects. In particular, the distributions were not generally exponential, and in some cases SNPs of smaller effect were less likely to segregate than SNPs of larger effect.

KW - Animal Breeding

KW - Genomics

KW - Quantitative Genetics (incl Disease and Trait Mapping Genetics)

UR - http://trove.nla.gov.au/work/36420775

UR - http://aaabg.org/aaabg18/

UR - http://www.aaabg.org/proceedings18/files/smith064.pdf

M3 - Conference contribution

SN - 9780646521039

VL - 18

SP - 65

EP - 67

BT - Proceedings of the Association for the Advancement of Animal Breeding and Genetics

A2 - Safari, Alex

A2 - Pattie, Bill

A2 - Restall, Barrie

PB - Association for the Advancement of Animal Breeding and Genetics (AAABG)

CY - Armidale, Australia

T2 - AAABG 2009: 18th Conference of the Association for the Advancement of Animal Breeding and Genetics

Y2 - 27 September 2009 through 2 October 2009

ER -

Variability in the Distributions of Single Nucleotide Polymorphism Effects in Livestock Populations

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Keywords

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