The Response of Sheep Vaccinated With Irradiated 'Trichostrongylus-Colubriformis' Larvae to Impulse and Sequential Challenge With Normal Larvae

Peter Gregg; J K Dineen

doi:10.1016/0304-4017(78)90035-3

The Response of Sheep Vaccinated With Irradiated 'Trichostrongylus-Colubriformis' Larvae to Impulse and Sequential Challenge With Normal Larvae

Peter Gregg, J K Dineen

School of Environmental & Rural Science

Research output: Contribution to journal › Article › peer-review

5 Citations (Scopus)

Abstract

Sheep aged 9-10 months were vaccinated with three doses of 20 000 irradiated 'Trichostrongylus colubriformis' larvae at fortnightly in tervals. This gave 97-99% protection against subsequent 'impulse' challenge with 40 000 normal larvae or 'sequential' challenge with 2 000 larvae/week-day for 4 weeks. The sheep were protected against both types of challenge when worms from the immunizing infections were present at the time of challenge, and when these worms were first removed by anthelmintic treatment.

Original language	English
Pages (from-to)	49-53
Journal	Veterinary Parasitology
Volume	4
Issue number	1
DOIs	https://doi.org/10.1016/0304-4017(78)90035-3
Publication status	Published - 1978

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This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Animal Protection (Pests and Pathogens)

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10.1016/0304-4017(78)90035-3

https://hdl.handle.net/1959.11/22214

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title = "The Response of Sheep Vaccinated With Irradiated 'Trichostrongylus-Colubriformis' Larvae to Impulse and Sequential Challenge With Normal Larvae",

abstract = "Sheep aged 9-10 months were vaccinated with three doses of 20 000 irradiated 'Trichostrongylus colubriformis' larvae at fortnightly in tervals. This gave 97-99\% protection against subsequent 'impulse' challenge with 40 000 normal larvae or 'sequential' challenge with 2 000 larvae/week-day for 4 weeks. The sheep were protected against both types of challenge when worms from the immunizing infections were present at the time of challenge, and when these worms were first removed by anthelmintic treatment.",

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AU - Gregg, Peter

AU - Dineen, J K

PY - 1978

Y1 - 1978

N2 - Sheep aged 9-10 months were vaccinated with three doses of 20 000 irradiated 'Trichostrongylus colubriformis' larvae at fortnightly in tervals. This gave 97-99% protection against subsequent 'impulse' challenge with 40 000 normal larvae or 'sequential' challenge with 2 000 larvae/week-day for 4 weeks. The sheep were protected against both types of challenge when worms from the immunizing infections were present at the time of challenge, and when these worms were first removed by anthelmintic treatment.

AB - Sheep aged 9-10 months were vaccinated with three doses of 20 000 irradiated 'Trichostrongylus colubriformis' larvae at fortnightly in tervals. This gave 97-99% protection against subsequent 'impulse' challenge with 40 000 normal larvae or 'sequential' challenge with 2 000 larvae/week-day for 4 weeks. The sheep were protected against both types of challenge when worms from the immunizing infections were present at the time of challenge, and when these worms were first removed by anthelmintic treatment.

KW - Animal Protection (Pests and Pathogens)

UR - https://www.scopus.com/pages/publications/49349119957

U2 - 10.1016/0304-4017(78)90035-3

DO - 10.1016/0304-4017(78)90035-3

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IS - 1

ER -

The Response of Sheep Vaccinated With Irradiated 'Trichostrongylus-Colubriformis' Larvae to Impulse and Sequential Challenge With Normal Larvae

Abstract

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