Abstract
An efficient method for the convergent assembly of MUC1-lipopeptide vaccine candidates is described. Chimeras consisting of MUC1 glycopeptides (bearing multiple copies of the TN and T tumour-associated carbohydrate antigens) tethered to the lipopeptide immunoadjuvant Pam3CysSer were synthesised in high yields using a fragment-based condensation strategy.
| Original language | English |
|---|---|
| Pages (from-to) | 6249-6251 |
| Journal | Chemical Communications |
| Volume | 46 |
| Issue number | 34 |
| DOIs | |
| Publication status | Published - 2010 |
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
-
SDG 3 Good Health and Well-being
Keywords
- Proteins and Peptides
- Biologically Active Molecules
- Organic Chemical Synthesis
Fingerprint
Dive into the research topics of 'Synthesis of MUC1-lipopeptide chimeras'. Together they form a unique fingerprint.Cite this
- APA
- Author
- BIBTEX
- Harvard
- Standard
- RIS
- Vancouver