Simple Example to Demonstrate the Effect of Allele Frequencies on the Genomic Relationship Matrix Values

M H Ferdosi; N K Connors; V Boerner; D J Johnston

Simple Example to Demonstrate the Effect of Allele Frequencies on the Genomic Relationship Matrix Values

M H Ferdosi, N K Connors, V Boerner, D J Johnston

Animal Genetics and Breeding Unit

Research output: Contribution to journal › Conference article › peer-review

Abstract

Genomic evaluations using single-step genomic best linear unbiased prediction (ssGBLUP) combine the genomic relationship matrix (GRM) and numerator relationship matrix (NRM) together, to form the H matrix. The GRM values represent relationships between individuals and are dependent on allele frequencies. In this study, a simple example is used to demonstrate how the change in allele frequency can effect the values in the GRM, while also exploring the possible range of GRM values.

Original language	English
Pages (from-to)	19-22
Journal	Proceedings of the Association for the Advancement of Animal Breeding and Genetics
Volume	23
Publication status	Published - 2019
Event	AAABG 2019: 23rd Conference of the Association for the Advancement of Animal Breeding and Genetics - University of New England, Armidale, Australia Duration: 27 Oct 2019 → 1 Nov 2019

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title = "Simple Example to Demonstrate the Effect of Allele Frequencies on the Genomic Relationship Matrix Values",

abstract = "Genomic evaluations using single-step genomic best linear unbiased prediction (ssGBLUP) combine the genomic relationship matrix (GRM) and numerator relationship matrix (NRM) together, to form the H matrix. The GRM values represent relationships between individuals and are dependent on allele frequencies. In this study, a simple example is used to demonstrate how the change in allele frequency can effect the values in the GRM, while also exploring the possible range of GRM values.",

author = "Ferdosi, \{M H\} and Connors, \{N K\} and V Boerner and Johnston, \{D J\}",

year = "2019",

language = "English",

volume = "23",

pages = "19--22",

journal = "Proceedings of the Association for the Advancement of Animal Breeding and Genetics",

issn = "1328-3227",

publisher = "Association for the Advancement of Animal Breeding and Genetics (AAABG)",

note = "AAABG 2019: 23rd Conference of the Association for the Advancement of Animal Breeding and Genetics ; Conference date: 27-10-2019 Through 01-11-2019",

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TY - JOUR

T1 - Simple Example to Demonstrate the Effect of Allele Frequencies on the Genomic Relationship Matrix Values

AU - Ferdosi, M H

AU - Connors, N K

AU - Boerner, V

AU - Johnston, D J

PY - 2019

Y1 - 2019

N2 - Genomic evaluations using single-step genomic best linear unbiased prediction (ssGBLUP) combine the genomic relationship matrix (GRM) and numerator relationship matrix (NRM) together, to form the H matrix. The GRM values represent relationships between individuals and are dependent on allele frequencies. In this study, a simple example is used to demonstrate how the change in allele frequency can effect the values in the GRM, while also exploring the possible range of GRM values.

AB - Genomic evaluations using single-step genomic best linear unbiased prediction (ssGBLUP) combine the genomic relationship matrix (GRM) and numerator relationship matrix (NRM) together, to form the H matrix. The GRM values represent relationships between individuals and are dependent on allele frequencies. In this study, a simple example is used to demonstrate how the change in allele frequency can effect the values in the GRM, while also exploring the possible range of GRM values.

UR - http://www.aaabg.org/aaabghome/

M3 - Conference article

SN - 1328-3227

VL - 23

SP - 19

EP - 22

JO - Proceedings of the Association for the Advancement of Animal Breeding and Genetics

JF - Proceedings of the Association for the Advancement of Animal Breeding and Genetics

T2 - AAABG 2019: 23rd Conference of the Association for the Advancement of Animal Breeding and Genetics

Y2 - 27 October 2019 through 1 November 2019

ER -

Simple Example to Demonstrate the Effect of Allele Frequencies on the Genomic Relationship Matrix Values

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