Abstract
Localized surface plasmon resonance (LSPR) is a promising detection method for label-free sensing of biomolecules. In this paper, a multilayer design for a LSPR biosensor is presented. In the proposed design, a periodic array of dielectric grating is incorporated on top of a graphene layer in the biosensor. The aim is to improve sensitivity of the LSPR biosensor through monitoring biomolecular interactions of biotin-streptavidin. Sensitivity improvement is obtained for the proposed LSPR biosensor compared with conventional SPR counterparts. In addition, to optimize the design, we have investigated grating geometry including volume factor and grating depth. The outcome of this investigation identifies ideal functioning conditions corresponding to the best design parameters.
| Original language | English |
|---|---|
| Title of host publication | Proceedings of the 2012 ICME International Conference on Complex Medical Engineering (CME) |
| Place of Publication | Los Alamitos, United States of America |
| Publisher | Institute of Electrical and Electronics Engineers (IEEE) |
| Pages | 490-494 |
| ISBN (Print) | 9781467316163, 9781467316170 |
| DOIs | |
| Publication status | Published - 2012 |
| Event | CME 2012: IEEE/ICME International Conference on Complex Medical Engineering - Kobe, Japan Duration: 1 Jul 2012 → 4 Jul 2012 |
Conference
| Conference | CME 2012: IEEE/ICME International Conference on Complex Medical Engineering |
|---|---|
| City | Kobe, Japan |
| Period | 1/07/12 → 4/07/12 |
Keywords
- Photonics and Electro-Optical Engineering (excl Communications)
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