Abstract
Pd-catalysed C-C bond formation is an essential tool within the pharmaceutical and agrochemical industries. Many of these reactions rely heavily on polar aprotic solvents; however, despite their utility, these solvents are incompatible with the drive towards more sustainable chemical synthesis. Herein, we describe the scope and limitations of an alternative to DMF derived from renewable sources (CyreneTM) in Sonogashira cross-coupling and Cacchi-type annulations.
| Original language | English |
|---|---|
| Pages (from-to) | 2005-2011 |
| Journal | Beilstein Journal of Organic Chemistry |
| Volume | 12 |
| DOIs | |
| Publication status | Published - 2016 |
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 7 Affordable and Clean Energy
Keywords
- Macromolecular and Materials Chemistry
- Organic Chemical Synthesis
- Organic Green Chemistry
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