Reply: On the Use of Odds Ratios Versus Hazard Ratios, Meta-Regression, and Heterogeneity in Meta-Analyses

We thank the editor of the Journal for the opportunity to respond to the letters by Dr. Shah, Dr. Ma and colleagues, and Dr. Zhao and colleagues, which all make similar statements about 3 aspects of the methodology used in our recent meta-analysis. As the points raised are sufficiently similar, we will address them as if they were derived from the same letter. First, the use of odds ratios instead of hazard ratios was raised in the letters to the editor.