QTL mapping for feed conversion efficiency on porcine chromosome 10 in an Australian commercial population

Y Chen; Yuandan Zhang; C Moran; I MacLeod; R Kerr; Kim L Bunter; B Hayes; Bruce Tier; Hans Graser; B G Luxford; M E Goddard

QTL mapping for feed conversion efficiency on porcine chromosome 10 in an Australian commercial population

Y Chen, Yuandan Zhang, C Moran, I MacLeod, R Kerr, Kim L Bunter, B Hayes, Bruce Tier, Hans Graser, B G Luxford, M E Goddard

Animal Genetics and Breeding Unit

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

Abstract

A genetic linkage map of 23 markers on porcine chromosome 10 was constructed with a resource pedigree based on an Australian commercial pig population. Six new markers (UMNP885, UMNP1049, UMNP875, UMNP925, UMNP876 and UMNP519) were linkage mapped to porcine chromosome 10 for the first time. Phenotypes were available for juvenile IGF-I along with feed intake, average daily gain and feed conversion ratio (FCR) recorded over a 6 week performance test period; associations between QTL and residuals for these traits were investigated. A significant QTL for FCR was found between marker UMNP875 and UMNP925 by single family and across family analysis with maximum likelihood using composite interval mapping, confirmed by linkage disequilibrum and linkage analysis (LDLA). In single family analyses, a significant QTL for average daily gain was found in sire family 896TS and an IGF-I QTL was found in sire family 52103. The study provided strong justification for further fine mapping and positional cloning of causative genes for FCR on chromosome 10 for marker assisted selection in pig breeding.

Original language	English
Title of host publication	Proceedings of the Association for the Advancement of Animal Breeding and Genetics
Editors	Alex Safari, Bill Pattie, Barrie Restall
Place of Publication	Armidale, Australia
Publisher	Association for the Advancement of Animal Breeding and Genetics (AAABG)
Pages	183-186
ISBN (Print)	9780646521039
Publication status	Published - 2009
Event	AAABG 2009: 18th Conference of the Association for the Advancement of Animal Breeding and Genetics - Barossa Valley, Australia Duration: 27 Sept 2009 → 2 Oct 2009

Conference

Conference	AAABG 2009: 18th Conference of the Association for the Advancement of Animal Breeding and Genetics
City	Barossa Valley, Australia
Period	27/09/09 → 2/10/09

Keywords

Animal Growth and Development
Animal Breeding

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Chen, Y., Zhang, Y., Moran, C., MacLeod, I., Kerr, R., Bunter, K. L., Hayes, B., Tier, B., Graser, H., Luxford, B. G., & Goddard, M. E. (2009). QTL mapping for feed conversion efficiency on porcine chromosome 10 in an Australian commercial population. In A. Safari, B. Pattie, & B. Restall (Eds.), Proceedings of the Association for the Advancement of Animal Breeding and Genetics (pp. 183-186). Association for the Advancement of Animal Breeding and Genetics (AAABG). https://hdl.handle.net/1959.11/5257

Chen, Y ; Zhang, Yuandan ; Moran, C et al. / QTL mapping for feed conversion efficiency on porcine chromosome 10 in an Australian commercial population. Proceedings of the Association for the Advancement of Animal Breeding and Genetics. editor / Alex Safari ; Bill Pattie ; Barrie Restall. Armidale, Australia : Association for the Advancement of Animal Breeding and Genetics (AAABG), 2009. pp. 183-186

@inproceedings{423c64be995941a991e5f43d93a27ab0,

title = "QTL mapping for feed conversion efficiency on porcine chromosome 10 in an Australian commercial population",

abstract = "A genetic linkage map of 23 markers on porcine chromosome 10 was constructed with a resource pedigree based on an Australian commercial pig population. Six new markers (UMNP885, UMNP1049, UMNP875, UMNP925, UMNP876 and UMNP519) were linkage mapped to porcine chromosome 10 for the first time. Phenotypes were available for juvenile IGF-I along with feed intake, average daily gain and feed conversion ratio (FCR) recorded over a 6 week performance test period; associations between QTL and residuals for these traits were investigated. A significant QTL for FCR was found between marker UMNP875 and UMNP925 by single family and across family analysis with maximum likelihood using composite interval mapping, confirmed by linkage disequilibrum and linkage analysis (LDLA). In single family analyses, a significant QTL for average daily gain was found in sire family 896TS and an IGF-I QTL was found in sire family 52103. The study provided strong justification for further fine mapping and positional cloning of causative genes for FCR on chromosome 10 for marker assisted selection in pig breeding.",

keywords = "Animal Growth and Development, Animal Breeding",

author = "Y Chen and Yuandan Zhang and C Moran and I MacLeod and R Kerr and Bunter, \{Kim L\} and B Hayes and Bruce Tier and Hans Graser and Luxford, \{B G\} and Goddard, \{M E\}",

year = "2009",

language = "English",

isbn = "9780646521039",

pages = "183--186",

editor = "Alex Safari and Bill Pattie and Barrie Restall",

booktitle = "Proceedings of the Association for the Advancement of Animal Breeding and Genetics",

publisher = "Association for the Advancement of Animal Breeding and Genetics (AAABG)",

note = "AAABG 2009: 18th Conference of the Association for the Advancement of Animal Breeding and Genetics ; Conference date: 27-09-2009 Through 02-10-2009",

}

Chen, Y, Zhang, Y, Moran, C, MacLeod, I, Kerr, R, Bunter, KL, Hayes, B, Tier, B, Graser, H, Luxford, BG & Goddard, ME 2009, QTL mapping for feed conversion efficiency on porcine chromosome 10 in an Australian commercial population. in A Safari, B Pattie & B Restall (eds), Proceedings of the Association for the Advancement of Animal Breeding and Genetics. Association for the Advancement of Animal Breeding and Genetics (AAABG), Armidale, Australia, pp. 183-186, AAABG 2009: 18th Conference of the Association for the Advancement of Animal Breeding and Genetics, Barossa Valley, Australia, 27/09/09. <https://hdl.handle.net/1959.11/5257>

QTL mapping for feed conversion efficiency on porcine chromosome 10 in an Australian commercial population. / Chen, Y; Zhang, Yuandan; Moran, C et al.
Proceedings of the Association for the Advancement of Animal Breeding and Genetics. ed. / Alex Safari; Bill Pattie; Barrie Restall. Armidale, Australia: Association for the Advancement of Animal Breeding and Genetics (AAABG), 2009. p. 183-186.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

TY - GEN

T1 - QTL mapping for feed conversion efficiency on porcine chromosome 10 in an Australian commercial population

AU - Chen, Y

AU - Zhang, Yuandan

AU - Moran, C

AU - MacLeod, I

AU - Kerr, R

AU - Bunter, Kim L

AU - Hayes, B

AU - Tier, Bruce

AU - Graser, Hans

AU - Luxford, B G

AU - Goddard, M E

PY - 2009

Y1 - 2009

N2 - A genetic linkage map of 23 markers on porcine chromosome 10 was constructed with a resource pedigree based on an Australian commercial pig population. Six new markers (UMNP885, UMNP1049, UMNP875, UMNP925, UMNP876 and UMNP519) were linkage mapped to porcine chromosome 10 for the first time. Phenotypes were available for juvenile IGF-I along with feed intake, average daily gain and feed conversion ratio (FCR) recorded over a 6 week performance test period; associations between QTL and residuals for these traits were investigated. A significant QTL for FCR was found between marker UMNP875 and UMNP925 by single family and across family analysis with maximum likelihood using composite interval mapping, confirmed by linkage disequilibrum and linkage analysis (LDLA). In single family analyses, a significant QTL for average daily gain was found in sire family 896TS and an IGF-I QTL was found in sire family 52103. The study provided strong justification for further fine mapping and positional cloning of causative genes for FCR on chromosome 10 for marker assisted selection in pig breeding.

AB - A genetic linkage map of 23 markers on porcine chromosome 10 was constructed with a resource pedigree based on an Australian commercial pig population. Six new markers (UMNP885, UMNP1049, UMNP875, UMNP925, UMNP876 and UMNP519) were linkage mapped to porcine chromosome 10 for the first time. Phenotypes were available for juvenile IGF-I along with feed intake, average daily gain and feed conversion ratio (FCR) recorded over a 6 week performance test period; associations between QTL and residuals for these traits were investigated. A significant QTL for FCR was found between marker UMNP875 and UMNP925 by single family and across family analysis with maximum likelihood using composite interval mapping, confirmed by linkage disequilibrum and linkage analysis (LDLA). In single family analyses, a significant QTL for average daily gain was found in sire family 896TS and an IGF-I QTL was found in sire family 52103. The study provided strong justification for further fine mapping and positional cloning of causative genes for FCR on chromosome 10 for marker assisted selection in pig breeding.

KW - Animal Growth and Development

KW - Animal Breeding

UR - http://www.aaabg.org/proceedings18/files/chen183.pdf

UR - http://aaabg.org/aaabg18/

UR - http://trove.nla.gov.au/work/36420775

M3 - Conference contribution

SN - 9780646521039

SP - 183

EP - 186

BT - Proceedings of the Association for the Advancement of Animal Breeding and Genetics

A2 - Safari, Alex

A2 - Pattie, Bill

A2 - Restall, Barrie

PB - Association for the Advancement of Animal Breeding and Genetics (AAABG)

CY - Armidale, Australia

T2 - AAABG 2009: 18th Conference of the Association for the Advancement of Animal Breeding and Genetics

Y2 - 27 September 2009 through 2 October 2009

ER -

Chen Y, Zhang Y, Moran C, MacLeod I, Kerr R, Bunter KL et al. QTL mapping for feed conversion efficiency on porcine chromosome 10 in an Australian commercial population. In Safari A, Pattie B, Restall B, editors, Proceedings of the Association for the Advancement of Animal Breeding and Genetics. Armidale, Australia: Association for the Advancement of Animal Breeding and Genetics (AAABG). 2009. p. 183-186

QTL mapping for feed conversion efficiency on porcine chromosome 10 in an Australian commercial population

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