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'N'-Heteroatom-substituted hydroxamic esters

  • Stephen Glover

    Research output: Chapter in Book/Report/Conference proceedingChapterResearch

    Abstract

    The properties of amides are determinants of the structure and characteristics of a wide range of molecules and particularly those of peptides and proteins. Hydroxamic esters, as a subset of the amide functionality, possess many structural features in common with the more abundant linkage. Amide linkages in hydroxamic esters and amides are characterized by a nitrogen that is essentially sp² hybridized and a lone pair that resides in a 2pz orbital.
    Original languageEnglish
    Title of host publicationThe Chemistry of Hydroxylamines, Oximes and Hydroxamic Acids
    EditorsZvi Rappoport, Joel Liebman
    Place of PublicationChichester, United Kingdom
    PublisherJohn Wiley & Sons Ltd
    Pages839-923
    Volume1
    Edition1
    ISBN (Print)047051261X, 9780470512616
    Publication statusPublished - 2009

    Publication series

    NamePatai Series: Functional Groups in Organic Chemistry

    Keywords

    • Organic Chemical Synthesis
    • Theoretical and Computational Chemistry
    • Physical Organic Chemistry

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