Abstract
This review will discuss the structural determinants and requirements necessary for estrogen receptors alpha and beta selectivity and ligand-receptor binding affinity. In addition, strategies likely to result in the development of a pharmacophore model that account for the differences in estrogenic effects between different ligands will be discussed.
| Original language | English |
|---|---|
| Pages (from-to) | 943-951 |
| Journal | Mini-Reviews in Medicinal Chemistry |
| Volume | 8 |
| Issue number | 9 |
| DOIs | |
| Publication status | Published - Aug 2008 |
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