Methyl 2,3,4-tri-O-acetyl-1-azido-1-deoxy-β-D-glucopyranuronate at room temperature

Brendan Wilkinson; Laurent F Bornaghi; Todd A Houston; Sally-Ann Poulsen; Peter C Healy

doi:10.1107/s1600536805004381

Methyl 2,3,4-tri-O-acetyl-1-azido-1-deoxy-β-D-glucopyranuronate at room temperature

Brendan Wilkinson, Laurent F Bornaghi, Todd A Houston, Sally-Ann Poulsen, Peter C Healy

Chemistry

Research output: Contribution to journal › Article › peer-review

4 Citations (Scopus)

Abstract

The structure of the title compound, C13H17N3O9, has been determined as part of our continuing investigation into the development of modified sugar amino acid (SAA) scaffolds for dynamic combinatorial libraries of cyclic oligomers. The title compound serves as a viable synthetic precursor and a building block for the synthesis of reversible [beta]-glucosidase inhibitors utilizing target-accelerated in situ click methodologies. The overall structure is stabilized by a number of C-H...O interactions.

Original language	English
Pages (from-to)	o738-o740
Journal	Acta crystallographica. Section E
Volume	61
Issue number	3
DOIs	https://doi.org/10.1107/s1600536805004381
Publication status	Published - 2005

Keywords

Organic Chemical Synthesis
Instrumental Methods (excl. Immunological and Bioassay Methods)

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https://hdl.handle.net/1959.11/22904

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title = "Methyl 2,3,4-tri-O-acetyl-1-azido-1-deoxy-β-D-glucopyranuronate at room temperature",

abstract = "The structure of the title compound, C13H17N3O9, has been determined as part of our continuing investigation into the development of modified sugar amino acid (SAA) scaffolds for dynamic combinatorial libraries of cyclic oligomers. The title compound serves as a viable synthetic precursor and a building block for the synthesis of reversible [beta]-glucosidase inhibitors utilizing target-accelerated in situ click methodologies. The overall structure is stabilized by a number of C-H...O interactions.",

keywords = "Organic Chemical Synthesis, Instrumental Methods (excl. Immunological and Bioassay Methods)",

author = "Brendan Wilkinson and Bornaghi, \{Laurent F\} and Houston, \{Todd A\} and Sally-Ann Poulsen and Healy, \{Peter C\}",

year = "2005",

doi = "10.1107/s1600536805004381",

language = "English",

volume = "61",

pages = "o738--o740",

journal = "Acta crystallographica. Section E",

issn = "1600-5368",

publisher = "International Union of Crystallography (IUCr)",

number = "3",

}

TY - JOUR

T1 - Methyl 2,3,4-tri-O-acetyl-1-azido-1-deoxy-β-D-glucopyranuronate at room temperature

AU - Wilkinson, Brendan

AU - Bornaghi, Laurent F

AU - Houston, Todd A

AU - Poulsen, Sally-Ann

AU - Healy, Peter C

PY - 2005

Y1 - 2005

N2 - The structure of the title compound, C13H17N3O9, has been determined as part of our continuing investigation into the development of modified sugar amino acid (SAA) scaffolds for dynamic combinatorial libraries of cyclic oligomers. The title compound serves as a viable synthetic precursor and a building block for the synthesis of reversible [beta]-glucosidase inhibitors utilizing target-accelerated in situ click methodologies. The overall structure is stabilized by a number of C-H...O interactions.

AB - The structure of the title compound, C13H17N3O9, has been determined as part of our continuing investigation into the development of modified sugar amino acid (SAA) scaffolds for dynamic combinatorial libraries of cyclic oligomers. The title compound serves as a viable synthetic precursor and a building block for the synthesis of reversible [beta]-glucosidase inhibitors utilizing target-accelerated in situ click methodologies. The overall structure is stabilized by a number of C-H...O interactions.

KW - Organic Chemical Synthesis

KW - Instrumental Methods (excl. Immunological and Bioassay Methods)

UR - https://www.scopus.com/pages/publications/18544384251

U2 - 10.1107/s1600536805004381

DO - 10.1107/s1600536805004381

M3 - Article

SN - 1600-5368

VL - 61

SP - o738-o740

JO - Acta crystallographica. Section E

JF - Acta crystallographica. Section E

IS - 3

ER -

Methyl 2,3,4-tri-O-acetyl-1-azido-1-deoxy-β-D-glucopyranuronate at room temperature

Abstract

Keywords

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