In vitro inhibitory activities of sugarcane extract on avian Eimeria sporozoites

Ali Daneshmand; Petrina Young; Bronwyn Campbell; Sarbast K Kheravii; Nishchal Kumar Sharma; Roya Afshari; Daniel A Dias; Matthew Flavel; Barry Kitchen; Shu-Biao Wu

doi:10.1016/j.ijpddr.2021.07.001

In vitro inhibitory activities of sugarcane extract on avian Eimeria sporozoites

Ali Daneshmand
, Petrina Young
, Bronwyn Campbell
, Sarbast K Kheravii
, Nishchal Kumar Sharma
, Roya Afshari
, Daniel A Dias
, Matthew Flavel
, Barry Kitchen
, Shu-Biao Wu

Research output: Contribution to journal › Article › peer-review

13 Citations (Scopus)

Abstract

The current in vitro study aimed to investigate the effects of a processed sugarcane extract on the viability of avian Eimeria sporozoites. Treatments were applied to hatched sporozoites: 1) without additives (no-treatment control); 2) with ethanol; 3) with salinomycin; 4) with Polygain™. All treatments were incubated in RPMI media containing live sporozoites at 37°C for 14 h and then the number of viable sporozoites were counted. Compared to the no-treatment control, Polygain™ decreased (P < 0.001) the counts of E. maxima, E. acervulina, E. bruneti, and E. mitis sporozoites to a level similar to salinomycin (P > 0.05). In conclusion, Polygain™ could be a potential candidate as an anticoccidial agent.

Original language	English
Pages (from-to)	1-4
Journal	International Journal for Parasitology: Drugs and Drug Resistance
Volume	17
Early online date	8 Jul 2021
DOIs	https://doi.org/10.1016/j.ijpddr.2021.07.001
Publication status	Published - Dec 2021

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10.1016/j.ijpddr.2021.07.001

https://hdl.handle.net/1959.11/31058Licence: CC BY-NC-ND

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title = "In vitro inhibitory activities of sugarcane extract on avian Eimeria sporozoites",

abstract = "The current in vitro study aimed to investigate the effects of a processed sugarcane extract on the viability of avian Eimeria sporozoites. Treatments were applied to hatched sporozoites: 1) without additives (no-treatment control); 2) with ethanol; 3) with salinomycin; 4) with Polygain{\texttrademark}. All treatments were incubated in RPMI media containing live sporozoites at 37°C for 14 h and then the number of viable sporozoites were counted. Compared to the no-treatment control, Polygain{\texttrademark} decreased (P < 0.001) the counts of E. maxima, E. acervulina, E. bruneti, and E. mitis sporozoites to a level similar to salinomycin (P > 0.05). In conclusion, Polygain{\texttrademark} could be a potential candidate as an anticoccidial agent.",

author = "Ali Daneshmand and Petrina Young and Bronwyn Campbell and Kheravii, \{Sarbast K\} and Sharma, \{Nishchal Kumar\} and Roya Afshari and Dias, \{Daniel A\} and Matthew Flavel and Barry Kitchen and Shu-Biao Wu",

year = "2021",

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doi = "10.1016/j.ijpddr.2021.07.001",

language = "English",

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journal = "International Journal for Parasitology: Drugs and Drug Resistance",

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T1 - In vitro inhibitory activities of sugarcane extract on avian Eimeria sporozoites

AU - Daneshmand, Ali

AU - Young, Petrina

AU - Campbell, Bronwyn

AU - Kheravii, Sarbast K

AU - Sharma, Nishchal Kumar

AU - Afshari, Roya

AU - Dias, Daniel A

AU - Flavel, Matthew

AU - Kitchen, Barry

AU - Wu, Shu-Biao

PY - 2021/12

Y1 - 2021/12

N2 - The current in vitro study aimed to investigate the effects of a processed sugarcane extract on the viability of avian Eimeria sporozoites. Treatments were applied to hatched sporozoites: 1) without additives (no-treatment control); 2) with ethanol; 3) with salinomycin; 4) with Polygain™. All treatments were incubated in RPMI media containing live sporozoites at 37°C for 14 h and then the number of viable sporozoites were counted. Compared to the no-treatment control, Polygain™ decreased (P < 0.001) the counts of E. maxima, E. acervulina, E. bruneti, and E. mitis sporozoites to a level similar to salinomycin (P > 0.05). In conclusion, Polygain™ could be a potential candidate as an anticoccidial agent.

AB - The current in vitro study aimed to investigate the effects of a processed sugarcane extract on the viability of avian Eimeria sporozoites. Treatments were applied to hatched sporozoites: 1) without additives (no-treatment control); 2) with ethanol; 3) with salinomycin; 4) with Polygain™. All treatments were incubated in RPMI media containing live sporozoites at 37°C for 14 h and then the number of viable sporozoites were counted. Compared to the no-treatment control, Polygain™ decreased (P < 0.001) the counts of E. maxima, E. acervulina, E. bruneti, and E. mitis sporozoites to a level similar to salinomycin (P > 0.05). In conclusion, Polygain™ could be a potential candidate as an anticoccidial agent.

U2 - 10.1016/j.ijpddr.2021.07.001

DO - 10.1016/j.ijpddr.2021.07.001

M3 - Article

SN - 2211-3207

VL - 17

SP - 1

EP - 4

JO - International Journal for Parasitology: Drugs and Drug Resistance

JF - International Journal for Parasitology: Drugs and Drug Resistance

ER -

In vitro inhibitory activities of sugarcane extract on avian Eimeria sporozoites

Abstract

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