Immunity to Helminth Infections

J K Dineen; R J Love; Peter Gregg; A D Donald; N Anderson; K C Bremner; R Fridemanis; J D Kelly; T L W Rothwell; W O Jones; B S Goodrich; I D Smith; G C Merritt; R S Hogarth-Scott; C C Curtain

Immunity to Helminth Infections

J K Dineen
, R J Love
, Peter Gregg
, A D Donald
, N Anderson
, K C Bremner
, R Fridemanis
, J D Kelly
, T L W Rothwell
, W O Jones
, B S Goodrich
, I D Smith
, G C Merritt
, R S Hogarth-Scott
, C C Curtain

School of Environmental & Rural Science

Research output: Chapter in Book/Report/Conference proceeding › Chapter › Other

Abstract

Vaccination with irradiated Trichostrongylus colubriformis larvae gave over 90% protection in mature sheep in pen studies, in which challenge with normal infective larvae was given either by impulse (a single large does of larvae) or sequentially (frequent smaller doses administered orally over a period of four weeks). Sequential challenge was designed to simulate the type of exposure to infective larvae likely to be encountered in the field. Vaccination was highly effective whether challenge infection was superimposed on the worm burden developed from the irradiated larvae or given after removal of the vaccine worm burden by anthelmintic treatment.

Original language	English
Title of host publication	CSIRO Division of Animal Health 1974
Editors	Commonwealth Scientific, Industrial Research Organization
Place of Publication	Australia
Publisher	Sheils Printing
Pages	75-83
Volume	1974
Publication status	Published - 1974

Publication series

Name	CSIRO:Division of Animal Health

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Animal Protection (Pests and Pathogens)

Access to Document

https://hdl.handle.net/1959.11/23328

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Dineen, J. K., Love, R. J., Gregg, P., Donald, A. D., Anderson, N., Bremner, K. C., Fridemanis, R., Kelly, J. D., Rothwell, T. L. W., Jones, W. O., Goodrich, B. S., Smith, I. D., Merritt, G. C., Hogarth-Scott, R. S., & Curtain, C. C. (1974). Immunity to Helminth Infections. In C. Scientific, & I. Research Organization (Eds.), CSIRO Division of Animal Health 1974 (Vol. 1974, pp. 75-83). (CSIRO:Division of Animal Health). Sheils Printing. https://hdl.handle.net/1959.11/23328

@inbook{80ae5e7c736d4cc4afb888fc5fe57cb3,

title = "Immunity to Helminth Infections",

abstract = "Vaccination with irradiated Trichostrongylus colubriformis larvae gave over 90\% protection in mature sheep in pen studies, in which challenge with normal infective larvae was given either by impulse (a single large does of larvae) or sequentially (frequent smaller doses administered orally over a period of four weeks). Sequential challenge was designed to simulate the type of exposure to infective larvae likely to be encountered in the field. Vaccination was highly effective whether challenge infection was superimposed on the worm burden developed from the irradiated larvae or given after removal of the vaccine worm burden by anthelmintic treatment.",

keywords = "Animal Protection (Pests and Pathogens)",

author = "Dineen, \{J K\} and Love, \{R J\} and Peter Gregg and Donald, \{A D\} and N Anderson and Bremner, \{K C\} and R Fridemanis and Kelly, \{J D\} and Rothwell, \{T L W\} and Jones, \{W O\} and Goodrich, \{B S\} and Smith, \{I D\} and Merritt, \{G C\} and Hogarth-Scott, \{R S\} and Curtain, \{C C\}",

year = "1974",

language = "English",

volume = "1974",

series = "CSIRO:Division of Animal Health",

publisher = "Sheils Printing",

pages = "75--83",

editor = "Commonwealth Scientific and \{Research Organization\}, Industrial",

booktitle = "CSIRO Division of Animal Health 1974",

}

Dineen, JK, Love, RJ, Gregg, P, Donald, AD, Anderson, N, Bremner, KC, Fridemanis, R, Kelly, JD, Rothwell, TLW, Jones, WO, Goodrich, BS, Smith, ID, Merritt, GC, Hogarth-Scott, RS & Curtain, CC 1974, Immunity to Helminth Infections. in C Scientific & I Research Organization (eds), CSIRO Division of Animal Health 1974. vol. 1974, CSIRO:Division of Animal Health, Sheils Printing, Australia, pp. 75-83. <https://hdl.handle.net/1959.11/23328>

TY - CHAP

T1 - Immunity to Helminth Infections

AU - Dineen, J K

AU - Love, R J

AU - Gregg, Peter

AU - Donald, A D

AU - Anderson, N

AU - Bremner, K C

AU - Fridemanis, R

AU - Kelly, J D

AU - Rothwell, T L W

AU - Jones, W O

AU - Goodrich, B S

AU - Smith, I D

AU - Merritt, G C

AU - Hogarth-Scott, R S

AU - Curtain, C C

PY - 1974

Y1 - 1974

N2 - Vaccination with irradiated Trichostrongylus colubriformis larvae gave over 90% protection in mature sheep in pen studies, in which challenge with normal infective larvae was given either by impulse (a single large does of larvae) or sequentially (frequent smaller doses administered orally over a period of four weeks). Sequential challenge was designed to simulate the type of exposure to infective larvae likely to be encountered in the field. Vaccination was highly effective whether challenge infection was superimposed on the worm burden developed from the irradiated larvae or given after removal of the vaccine worm burden by anthelmintic treatment.

AB - Vaccination with irradiated Trichostrongylus colubriformis larvae gave over 90% protection in mature sheep in pen studies, in which challenge with normal infective larvae was given either by impulse (a single large does of larvae) or sequentially (frequent smaller doses administered orally over a period of four weeks). Sequential challenge was designed to simulate the type of exposure to infective larvae likely to be encountered in the field. Vaccination was highly effective whether challenge infection was superimposed on the worm burden developed from the irradiated larvae or given after removal of the vaccine worm burden by anthelmintic treatment.

KW - Animal Protection (Pests and Pathogens)

UR - https://publications.csiro.au/rpr/pub?list=SEA&pid=procite:8ee3e598-4376-48e6-a442-3c0ed658a4f3&sb=RECENT&expert=false&n=1&rpp=25&page=1&tr=2&q=IMMUNITY%20TO%20HELMINTH%20INFECTIONS&dr=all

M3 - Chapter

VL - 1974

T3 - CSIRO:Division of Animal Health

SP - 75

EP - 83

BT - CSIRO Division of Animal Health 1974

A2 - Scientific, Commonwealth

A2 - Research Organization, Industrial

PB - Sheils Printing

CY - Australia

ER -

Immunity to Helminth Infections

Abstract

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UN SDGs

Keywords

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