Gut Microbiome and Depression: Bidirectional Communication and Implications for Treatment

Gal Winter; Robert A Hart; Richard P G Charlesworth; Christopher Sharpley

doi:10.1093/oxfordhb/9780190931544.013.6

Gut Microbiome and Depression: Bidirectional Communication and Implications for Treatment

Gal Winter
, Robert A Hart
, Richard P G Charlesworth
, Christopher Sharpley

Biomedical Science

Research output: Chapter in Book/Report/Conference proceeding › Chapter › Research › peer-review

Abstract

Gut microbial diversity has been strongly associated with mood-related behaviors, including major depressive disorder (MDD), with an emerging potential to revolutionize both the diagnosis and treatment of depression. This article reviews the communication systems between the gut and the brain and the association between gut inflammatory conditions and depression. It further reviews the role of the gut microbiota in the treatment of depression, from pharmacological treatment to the use of probiotics and dietary treatments.

Original language	English
Title of host publication	The Oxford Handbook of the Microbiome-Gut-Brain Axis
Editors	Philip W J Burnet
Place of Publication	Oxford, United Kingdom
Publisher	Oxford University Press
Pages	1-31
Edition	1
ISBN (Print)	9780190931544
DOIs	https://doi.org/10.1093/oxfordhb/9780190931544.013.6
Publication status	Published - 31 Jul 2020

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This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

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10.1093/oxfordhb/9780190931544.013.6

https://hdl.handle.net/1959.11/29508

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abstract = "Gut microbial diversity has been strongly associated with mood-related behaviors, including major depressive disorder (MDD), with an emerging potential to revolutionize both the diagnosis and treatment of depression. This article reviews the communication systems between the gut and the brain and the association between gut inflammatory conditions and depression. It further reviews the role of the gut microbiota in the treatment of depression, from pharmacological treatment to the use of probiotics and dietary treatments.",

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Gut Microbiome and Depression: Bidirectional Communication and Implications for Treatment. / Winter, Gal; Hart, Robert A; Charlesworth, Richard P G et al.
The Oxford Handbook of the Microbiome-Gut-Brain Axis. ed. / Philip W J Burnet. 1. ed. Oxford, United Kingdom: Oxford University Press, 2020. p. 1-31.

Research output: Chapter in Book/Report/Conference proceeding › Chapter › Research › peer-review

TY - CHAP

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AU - Hart, Robert A

AU - Charlesworth, Richard P G

AU - Sharpley, Christopher

PY - 2020/7/31

Y1 - 2020/7/31

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AB - Gut microbial diversity has been strongly associated with mood-related behaviors, including major depressive disorder (MDD), with an emerging potential to revolutionize both the diagnosis and treatment of depression. This article reviews the communication systems between the gut and the brain and the association between gut inflammatory conditions and depression. It further reviews the role of the gut microbiota in the treatment of depression, from pharmacological treatment to the use of probiotics and dietary treatments.

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BT - The Oxford Handbook of the Microbiome-Gut-Brain Axis

A2 - Burnet, Philip W J

PB - Oxford University Press

CY - Oxford, United Kingdom

ER -

Gut Microbiome and Depression: Bidirectional Communication and Implications for Treatment

Abstract

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