TY - CHAP
T1 - Genomic Selection in Animal Breeding Programs
AU - Van Der Werf, Julius H
PY - 2013
Y1 - 2013
N2 - Genomic selection can have a major impact on animal breeding programs, especially where traits that are important in the breeding objective are hard to select for otherwise. Genomic selection provides more accurate estimates for breeding value earlier in the life of breeding animals, giving more selection accuracy and allowing lower generation intervals. From sheep to dairy cattle, the rates of genetic improvement could increase from 20 to 100 % and hard-to-measure traits can be improved more effectively. Reference populations for genomic selection need to be large, with thousands of animals measured for phenotype and genotype. The smaller the effective size of the breeding population, the larger the DNA segments they potentially share and the more accurate genomic prediction will be. The relative contribution of information from relatives in the reference population will be larger if the baseline accuracy is low, but such information is limited to closely related individuals and does not last over generations.
AB - Genomic selection can have a major impact on animal breeding programs, especially where traits that are important in the breeding objective are hard to select for otherwise. Genomic selection provides more accurate estimates for breeding value earlier in the life of breeding animals, giving more selection accuracy and allowing lower generation intervals. From sheep to dairy cattle, the rates of genetic improvement could increase from 20 to 100 % and hard-to-measure traits can be improved more effectively. Reference populations for genomic selection need to be large, with thousands of animals measured for phenotype and genotype. The smaller the effective size of the breeding population, the larger the DNA segments they potentially share and the more accurate genomic prediction will be. The relative contribution of information from relatives in the reference population will be larger if the baseline accuracy is low, but such information is limited to closely related individuals and does not last over generations.
KW - Quantitative Genetics (incl Disease and Trait Mapping Genetics)
UR - http://trove.nla.gov.au/version/198468706
UR - https://www.scopus.com/pages/publications/84883188809
U2 - 10.1007/978-1-62703-447-0_26
DO - 10.1007/978-1-62703-447-0_26
M3 - Chapter
SN - 9781627034470
SN - 9781627034463
T3 - Methods in Molecular Biology
SP - 543
EP - 561
BT - Genome-Wide Association Studies and Genomic Prediction
A2 - Gondro, Cedric
A2 - van der Werf, Julius
A2 - Hayes, Ben
PB - Humana Press
CY - New York, United States of America
ER -