Functional genomics of estimated breeding value for eye muscle depth in sheep

L J A Kogelman; N S Watson-Haigh; H N Kadarmideen; J W Kijas; T Vuocolo; K Byrne; Hutton Oddy; Graham E Gardner; Cedric Gondro; R L Tellam

Functional genomics of estimated breeding value for eye muscle depth in sheep

L J A Kogelman
, N S Watson-Haigh
, H N Kadarmideen
, J W Kijas
, T Vuocolo
, K Byrne
, Hutton Oddy
, Graham E Gardner
, Cedric Gondro
, R L Tellam

School of Environmental & Rural Science

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

Abstract

A weighted gene co-expression network analysis (WGCN) and a differential network analysis were applied to microarray gene expression data for skeletal muscle samples from progeny of 6 Poll Dorset sires characterised as having high or low estimated breeding values (EBVs) for Eye Muscle Depth (EMD). There was strong genetic architecture to the gene expression data. Gene network analyses identified expression modules that were enriched for several biological themes including protein catabolism, ribosome function, mRNA processing, mitochondria and muscle structural proteins. These biological pathways likely contribute to the genetics of enhanced muscling in sheep.

Original language	English
Title of host publication	Proceedings of the Association for the Advancement of Animal Breeding and Genetics
Editors	William Pattie
Place of Publication	Armidale, Australia
Publisher	Association for the Advancement of Animal Breeding and Genetics (AAABG)
Pages	462-465
Volume	19
ISBN (Print)	9780646559155
Publication status	Published - 2011
Event	AAABG 2011: 19th Conference of the Association for the Advancement of Animal Breeding and Genetics - Perth, Australia Duration: 19 Jul 2011 → 21 Jul 2011

Conference

Conference	AAABG 2011: 19th Conference of the Association for the Advancement of Animal Breeding and Genetics
City	Perth, Australia
Period	19/07/11 → 21/07/11

Keywords

Animal Breeding

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https://hdl.handle.net/1959.11/10087

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Kogelman, L. J. A., Watson-Haigh, N. S., Kadarmideen, H. N., Kijas, J. W., Vuocolo, T., Byrne, K., Oddy, H., Gardner, G. E., Gondro, C., & Tellam, R. L. (2011). Functional genomics of estimated breeding value for eye muscle depth in sheep. In W. Pattie (Ed.), Proceedings of the Association for the Advancement of Animal Breeding and Genetics (Vol. 19, pp. 462-465). Association for the Advancement of Animal Breeding and Genetics (AAABG). https://hdl.handle.net/1959.11/10087

Kogelman, L J A ; Watson-Haigh, N S ; Kadarmideen, H N et al. / Functional genomics of estimated breeding value for eye muscle depth in sheep. Proceedings of the Association for the Advancement of Animal Breeding and Genetics. editor / William Pattie. Vol. 19 Armidale, Australia : Association for the Advancement of Animal Breeding and Genetics (AAABG), 2011. pp. 462-465

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title = "Functional genomics of estimated breeding value for eye muscle depth in sheep",

abstract = "A weighted gene co-expression network analysis (WGCN) and a differential network analysis were applied to microarray gene expression data for skeletal muscle samples from progeny of 6 Poll Dorset sires characterised as having high or low estimated breeding values (EBVs) for Eye Muscle Depth (EMD). There was strong genetic architecture to the gene expression data. Gene network analyses identified expression modules that were enriched for several biological themes including protein catabolism, ribosome function, mRNA processing, mitochondria and muscle structural proteins. These biological pathways likely contribute to the genetics of enhanced muscling in sheep.",

keywords = "Animal Breeding",

author = "Kogelman, \{L J A\} and Watson-Haigh, \{N S\} and Kadarmideen, \{H N\} and Kijas, \{J W\} and T Vuocolo and K Byrne and Hutton Oddy and Gardner, \{Graham E\} and Cedric Gondro and Tellam, \{R L\}",

year = "2011",

language = "English",

isbn = "9780646559155",

volume = "19",

pages = "462--465",

editor = "William Pattie",

booktitle = "Proceedings of the Association for the Advancement of Animal Breeding and Genetics",

publisher = "Association for the Advancement of Animal Breeding and Genetics (AAABG)",

note = "AAABG 2011: 19th Conference of the Association for the Advancement of Animal Breeding and Genetics ; Conference date: 19-07-2011 Through 21-07-2011",

}

Kogelman, LJA, Watson-Haigh, NS, Kadarmideen, HN, Kijas, JW, Vuocolo, T, Byrne, K, Oddy, H, Gardner, GE, Gondro, C & Tellam, RL 2011, Functional genomics of estimated breeding value for eye muscle depth in sheep. in W Pattie (ed.), Proceedings of the Association for the Advancement of Animal Breeding and Genetics. vol. 19, Association for the Advancement of Animal Breeding and Genetics (AAABG), Armidale, Australia, pp. 462-465, AAABG 2011: 19th Conference of the Association for the Advancement of Animal Breeding and Genetics, Perth, Australia, 19/07/11. <https://hdl.handle.net/1959.11/10087>

Functional genomics of estimated breeding value for eye muscle depth in sheep. / Kogelman, L J A; Watson-Haigh, N S; Kadarmideen, H N et al.
Proceedings of the Association for the Advancement of Animal Breeding and Genetics. ed. / William Pattie. Vol. 19 Armidale, Australia: Association for the Advancement of Animal Breeding and Genetics (AAABG), 2011. p. 462-465.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

TY - GEN

T1 - Functional genomics of estimated breeding value for eye muscle depth in sheep

AU - Kogelman, L J A

AU - Watson-Haigh, N S

AU - Kadarmideen, H N

AU - Kijas, J W

AU - Vuocolo, T

AU - Byrne, K

AU - Oddy, Hutton

AU - Gardner, Graham E

AU - Gondro, Cedric

AU - Tellam, R L

PY - 2011

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N2 - A weighted gene co-expression network analysis (WGCN) and a differential network analysis were applied to microarray gene expression data for skeletal muscle samples from progeny of 6 Poll Dorset sires characterised as having high or low estimated breeding values (EBVs) for Eye Muscle Depth (EMD). There was strong genetic architecture to the gene expression data. Gene network analyses identified expression modules that were enriched for several biological themes including protein catabolism, ribosome function, mRNA processing, mitochondria and muscle structural proteins. These biological pathways likely contribute to the genetics of enhanced muscling in sheep.

AB - A weighted gene co-expression network analysis (WGCN) and a differential network analysis were applied to microarray gene expression data for skeletal muscle samples from progeny of 6 Poll Dorset sires characterised as having high or low estimated breeding values (EBVs) for Eye Muscle Depth (EMD). There was strong genetic architecture to the gene expression data. Gene network analyses identified expression modules that were enriched for several biological themes including protein catabolism, ribosome function, mRNA processing, mitochondria and muscle structural proteins. These biological pathways likely contribute to the genetics of enhanced muscling in sheep.

KW - Animal Breeding

UR - http://trove.nla.gov.au/work/162660639

UR - http://www.aaabg.org/aaabg19/

M3 - Conference contribution

SN - 9780646559155

VL - 19

SP - 462

EP - 465

BT - Proceedings of the Association for the Advancement of Animal Breeding and Genetics

A2 - Pattie, William

PB - Association for the Advancement of Animal Breeding and Genetics (AAABG)

CY - Armidale, Australia

T2 - AAABG 2011: 19th Conference of the Association for the Advancement of Animal Breeding and Genetics

Y2 - 19 July 2011 through 21 July 2011

ER -

Kogelman LJA, Watson-Haigh NS, Kadarmideen HN, Kijas JW, Vuocolo T, Byrne K et al. Functional genomics of estimated breeding value for eye muscle depth in sheep. In Pattie W, editor, Proceedings of the Association for the Advancement of Animal Breeding and Genetics. Vol. 19. Armidale, Australia: Association for the Advancement of Animal Breeding and Genetics (AAABG). 2011. p. 462-465

Functional genomics of estimated breeding value for eye muscle depth in sheep

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Keywords

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