Abstract
Hepatitis E virus (HEV) is an important cause of acute hepatitis in humans. Zoonotic transmission between pigs and humans has been confirmed. Human HEV infection is common in Nigeria; however, characterization of HEV infection in other species was lacking. The objective of this study was to investigate HEV infection in Nigerian pigs. A total of 286 serum samples from six states in Nigeria were tested for presence of anti-HEV IgG. Ninety fecal samples from one of these states (Plateau State) were tested for presence of HEV RNA. The overall prevalence of anti-HEV IgG-positive or suspect-positive pigs was 55.6% (159 of 286) with regional prevalence rates ranging from 36% (9 of 25; Delta State) to 88% (22 of 25; Taraba State). The overall HEV RNA prevalence rate was 76.7% (69 of 90). All polymerase chain reaction-positive samples belonged to HEV genotype 3 based on sequencing. The results indicate that HEV genotype 3 infection is widespread in Nigerian pigs.
| Original language | English |
|---|---|
| Pages (from-to) | 699-704 |
| Journal | American Journal of Tropical Medicine and Hygiene |
| Volume | 91 |
| Issue number | 4 |
| DOIs | |
| Publication status | Published - 2014 |
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 3 Good Health and Well-being
Keywords
- Veterinary Virology
- Veterinary Diagnosis and Diagnostics
- Veterinary Epidemiology
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