Extent of linkage disequilibrium and haplotype blocks in bovine genome using high density SNP markers

M S Khatkar; K R Zenger; J A L Cavanagh; R J Hawken; M Hobbs; W Barris; P C Thomson; FW Nicholas; Bruce Tier; H W Raadsma

Extent of linkage disequilibrium and haplotype blocks in bovine genome using high density SNP markers

M S Khatkar
, K R Zenger
, J A L Cavanagh
, R J Hawken
, M Hobbs
, W Barris
, P C Thomson
, FW Nicholas
, Bruce Tier
, H W Raadsma

Animal Genetics and Breeding Unit

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

Abstract

A haplotype block map of the bovine genome was constructed based on the analysis of 15,036 SNPs on 1,000 un-related bulls. This map identified a total of 727 haplotype blocks consisting of three or more SNPs. These blocks have a mean length of 69.7 kb and cover 2.2 % of the length of all autosomes. This analysis suggested that approximately 250,000 SNPs would be required to prepare a complete haplotype block map of the bovine genome with 75,000 tag SNPs

Original language	English
Title of host publication	Proceedings of the Seventeenth Conference for the Advancement of Animal Breeding and Genetics
Editors	AAABG: Association for the Advancement of Animal Breeding, Genetics
Place of Publication	Armidale, Australia
Publisher	Association for the Advancement of Animal Breeding and Genetics (AAABG)
Pages	215-218
Volume	17
ISBN (Print)	1921208139
Publication status	Published - 2007
Event	AAABG 2007: 17th Conference of the Association for the Advancement of Animal Breeding and Genetics - University of New England, Armidale, Australia Duration: 23 Sept 2007 → 26 Sept 2007

Conference

Conference	AAABG 2007: 17th Conference of the Association for the Advancement of Animal Breeding and Genetics
City	Armidale, Australia
Period	23/09/07 → 26/09/07

Keywords

Quantitative Genetics (incl Disease and Trait Mapping Genetics)

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https://hdl.handle.net/1959.11/4157

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Khatkar, M. S., Zenger, K. R., Cavanagh, J. A. L., Hawken, R. J., Hobbs, M., Barris, W., Thomson, P. C., Nicholas, FW., Tier, B., & Raadsma, H. W. (2007). Extent of linkage disequilibrium and haplotype blocks in bovine genome using high density SNP markers. In AAABG. Association for the Advancement of Animal Breeding, & Genetics (Eds.), Proceedings of the Seventeenth Conference for the Advancement of Animal Breeding and Genetics (Vol. 17, pp. 215-218). Association for the Advancement of Animal Breeding and Genetics (AAABG). https://hdl.handle.net/1959.11/4157

Khatkar, M S ; Zenger, K R ; Cavanagh, J A L et al. / Extent of linkage disequilibrium and haplotype blocks in bovine genome using high density SNP markers. Proceedings of the Seventeenth Conference for the Advancement of Animal Breeding and Genetics. editor / AAABG: Association for the Advancement of Animal Breeding ; Genetics. Vol. 17 Armidale, Australia : Association for the Advancement of Animal Breeding and Genetics (AAABG), 2007. pp. 215-218

@inproceedings{61da514f46894074a69eeec12f65f59a,

title = "Extent of linkage disequilibrium and haplotype blocks in bovine genome using high density SNP markers",

abstract = "A haplotype block map of the bovine genome was constructed based on the analysis of 15,036 SNPs on 1,000 un-related bulls. This map identified a total of 727 haplotype blocks consisting of three or more SNPs. These blocks have a mean length of 69.7 kb and cover 2.2 \% of the length of all autosomes. This analysis suggested that approximately 250,000 SNPs would be required to prepare a complete haplotype block map of the bovine genome with 75,000 tag SNPs",

keywords = "Quantitative Genetics (incl Disease and Trait Mapping Genetics)",

author = "Khatkar, \{M S\} and Zenger, \{K R\} and Cavanagh, \{J A L\} and Hawken, \{R J\} and M Hobbs and W Barris and Thomson, \{P C\} and FW Nicholas and Bruce Tier and Raadsma, \{H W\}",

year = "2007",

language = "English",

isbn = "1921208139",

volume = "17",

pages = "215--218",

editor = "\{Association for the Advancement of Animal Breeding\}, AAABG: and Genetics",

booktitle = "Proceedings of the Seventeenth Conference for the Advancement of Animal Breeding and Genetics",

publisher = "Association for the Advancement of Animal Breeding and Genetics (AAABG)",

note = "AAABG 2007: 17th Conference of the Association for the Advancement of Animal Breeding and Genetics ; Conference date: 23-09-2007 Through 26-09-2007",

}

Khatkar, MS, Zenger, KR, Cavanagh, JAL, Hawken, RJ, Hobbs, M, Barris, W, Thomson, PC, Nicholas, FW, Tier, B & Raadsma, HW 2007, Extent of linkage disequilibrium and haplotype blocks in bovine genome using high density SNP markers. in AAABG Association for the Advancement of Animal Breeding & Genetics (eds), Proceedings of the Seventeenth Conference for the Advancement of Animal Breeding and Genetics. vol. 17, Association for the Advancement of Animal Breeding and Genetics (AAABG), Armidale, Australia, pp. 215-218, AAABG 2007: 17th Conference of the Association for the Advancement of Animal Breeding and Genetics, Armidale, Australia, 23/09/07. <https://hdl.handle.net/1959.11/4157>

Extent of linkage disequilibrium and haplotype blocks in bovine genome using high density SNP markers. / Khatkar, M S; Zenger, K R; Cavanagh, J A L et al.
Proceedings of the Seventeenth Conference for the Advancement of Animal Breeding and Genetics. ed. / AAABG: Association for the Advancement of Animal Breeding; Genetics. Vol. 17 Armidale, Australia: Association for the Advancement of Animal Breeding and Genetics (AAABG), 2007. p. 215-218.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

TY - GEN

T1 - Extent of linkage disequilibrium and haplotype blocks in bovine genome using high density SNP markers

AU - Khatkar, M S

AU - Zenger, K R

AU - Cavanagh, J A L

AU - Hawken, R J

AU - Hobbs, M

AU - Barris, W

AU - Thomson, P C

AU - Nicholas, FW

AU - Tier, Bruce

AU - Raadsma, H W

PY - 2007

Y1 - 2007

N2 - A haplotype block map of the bovine genome was constructed based on the analysis of 15,036 SNPs on 1,000 un-related bulls. This map identified a total of 727 haplotype blocks consisting of three or more SNPs. These blocks have a mean length of 69.7 kb and cover 2.2 % of the length of all autosomes. This analysis suggested that approximately 250,000 SNPs would be required to prepare a complete haplotype block map of the bovine genome with 75,000 tag SNPs

AB - A haplotype block map of the bovine genome was constructed based on the analysis of 15,036 SNPs on 1,000 un-related bulls. This map identified a total of 727 haplotype blocks consisting of three or more SNPs. These blocks have a mean length of 69.7 kb and cover 2.2 % of the length of all autosomes. This analysis suggested that approximately 250,000 SNPs would be required to prepare a complete haplotype block map of the bovine genome with 75,000 tag SNPs

KW - Quantitative Genetics (incl Disease and Trait Mapping Genetics)

UR - http://trove.nla.gov.au/work/35062558?selectedversion=NBD42373479

UR - http://www.aaabg.org/livestocklibrary/2007/khatkar215.pdf

M3 - Conference contribution

SN - 1921208139

VL - 17

SP - 215

EP - 218

BT - Proceedings of the Seventeenth Conference for the Advancement of Animal Breeding and Genetics

A2 - Association for the Advancement of Animal Breeding, AAABG:

A2 - Genetics, null

PB - Association for the Advancement of Animal Breeding and Genetics (AAABG)

CY - Armidale, Australia

T2 - AAABG 2007: 17th Conference of the Association for the Advancement of Animal Breeding and Genetics

Y2 - 23 September 2007 through 26 September 2007

ER -

Khatkar MS, Zenger KR, Cavanagh JAL, Hawken RJ, Hobbs M, Barris W et al. Extent of linkage disequilibrium and haplotype blocks in bovine genome using high density SNP markers. In Association for the Advancement of Animal Breeding AAABG, Genetics, editors, Proceedings of the Seventeenth Conference for the Advancement of Animal Breeding and Genetics. Vol. 17. Armidale, Australia: Association for the Advancement of Animal Breeding and Genetics (AAABG). 2007. p. 215-218

Extent of linkage disequilibrium and haplotype blocks in bovine genome using high density SNP markers

Abstract

Conference

Keywords

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