Estimating genetic merit when genotype data are incomplete

Bruce Tier; Kim Louise Bunter

Estimating genetic merit when genotype data are incomplete

Bruce Tier
, Kim Louise Bunter

Animal Genetics and Breeding Unit

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

Abstract

Direct markers for QTL are becoming available and, for traits that are difficult to measure or observed later in life, offer the potential to increase the accuracy of EBVs. While genotyping costs are non-trivial, QTL information will not be available for all individuals - with important consequences for genetic evaluation systems. Using simulated populations in which all parents and some progeny are genotyped for a QTL acting additively, two methods of using genotypic information are compared with EBVs based on the infintessimal model. Both methods - deregressing EBVs for the QTL effect according to their accuracy, or using heterogeneous residual variances - improve correlations between simulated and estimated genetic merit, particularly for individuals without performance data.

Original language	English
Title of host publication	Proceedings of the Association for the Advancement of Animal Breeding and Genetics
Editors	Abigail Henderson
Place of Publication	Armidale, Australia
Publisher	Association for the Advancement of Animal Breeding and Genetics (AAABG)
Pages	214-217
Volume	15
ISBN (Print)	0958629927
Publication status	Published - 2003
Event	AAABG 2003: 15th Conference of the Association for the Advancement of Animal Breeding and Genetics - Melbourne, Australia Duration: 7 Jul 2003 → 11 Jul 2003

Conference

Conference	AAABG 2003: 15th Conference of the Association for the Advancement of Animal Breeding and Genetics
City	Melbourne, Australia
Period	7/07/03 → 11/07/03

Keywords

Animal Breeding

Access to Document

https://hdl.handle.net/1959.11/4352

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Cite this

@inproceedings{80f12557bbec4fdfbddfee9ec7f70ee7,

title = "Estimating genetic merit when genotype data are incomplete",

abstract = "Direct markers for QTL are becoming available and, for traits that are difficult to measure or observed later in life, offer the potential to increase the accuracy of EBVs. While genotyping costs are non-trivial, QTL information will not be available for all individuals - with important consequences for genetic evaluation systems. Using simulated populations in which all parents and some progeny are genotyped for a QTL acting additively, two methods of using genotypic information are compared with EBVs based on the infintessimal model. Both methods - deregressing EBVs for the QTL effect according to their accuracy, or using heterogeneous residual variances - improve correlations between simulated and estimated genetic merit, particularly for individuals without performance data.",

keywords = "Animal Breeding",

author = "Bruce Tier and Bunter, \{Kim Louise\}",

year = "2003",

language = "English",

isbn = "0958629927",

volume = "15",

pages = "214--217",

editor = "Abigail Henderson",

booktitle = "Proceedings of the Association for the Advancement of Animal Breeding and Genetics",

publisher = "Association for the Advancement of Animal Breeding and Genetics (AAABG)",

note = "AAABG 2003: 15th Conference of the Association for the Advancement of Animal Breeding and Genetics ; Conference date: 07-07-2003 Through 11-07-2003",

}

Tier, B & Bunter, KL 2003, Estimating genetic merit when genotype data are incomplete. in A Henderson (ed.), Proceedings of the Association for the Advancement of Animal Breeding and Genetics. vol. 15, Association for the Advancement of Animal Breeding and Genetics (AAABG), Armidale, Australia, pp. 214-217, AAABG 2003: 15th Conference of the Association for the Advancement of Animal Breeding and Genetics, Melbourne, Australia, 7/07/03. <https://hdl.handle.net/1959.11/4352>

Estimating genetic merit when genotype data are incomplete. / Tier, Bruce; Bunter, Kim Louise.
Proceedings of the Association for the Advancement of Animal Breeding and Genetics. ed. / Abigail Henderson. Vol. 15 Armidale, Australia: Association for the Advancement of Animal Breeding and Genetics (AAABG), 2003. p. 214-217.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

TY - GEN

T1 - Estimating genetic merit when genotype data are incomplete

AU - Tier, Bruce

AU - Bunter, Kim Louise

PY - 2003

Y1 - 2003

N2 - Direct markers for QTL are becoming available and, for traits that are difficult to measure or observed later in life, offer the potential to increase the accuracy of EBVs. While genotyping costs are non-trivial, QTL information will not be available for all individuals - with important consequences for genetic evaluation systems. Using simulated populations in which all parents and some progeny are genotyped for a QTL acting additively, two methods of using genotypic information are compared with EBVs based on the infintessimal model. Both methods - deregressing EBVs for the QTL effect according to their accuracy, or using heterogeneous residual variances - improve correlations between simulated and estimated genetic merit, particularly for individuals without performance data.

AB - Direct markers for QTL are becoming available and, for traits that are difficult to measure or observed later in life, offer the potential to increase the accuracy of EBVs. While genotyping costs are non-trivial, QTL information will not be available for all individuals - with important consequences for genetic evaluation systems. Using simulated populations in which all parents and some progeny are genotyped for a QTL acting additively, two methods of using genotypic information are compared with EBVs based on the infintessimal model. Both methods - deregressing EBVs for the QTL effect according to their accuracy, or using heterogeneous residual variances - improve correlations between simulated and estimated genetic merit, particularly for individuals without performance data.

KW - Animal Breeding

UR - http://trove.nla.gov.au/work/22223828?selectedversion=NBD24379203

UR - http://www.aaabg.org/livestocklibrary/2003/214-217.pdf

M3 - Conference contribution

SN - 0958629927

VL - 15

SP - 214

EP - 217

BT - Proceedings of the Association for the Advancement of Animal Breeding and Genetics

A2 - Henderson, Abigail

PB - Association for the Advancement of Animal Breeding and Genetics (AAABG)

CY - Armidale, Australia

T2 - AAABG 2003: 15th Conference of the Association for the Advancement of Animal Breeding and Genetics

Y2 - 7 July 2003 through 11 July 2003

ER -

Estimating genetic merit when genotype data are incomplete

Abstract

Conference

Keywords

Access to Document

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Cite this