Effects of lung volume on airway closure during recovery from acute severe asthma

Tom van der Touw

doi:10.1111/j.1440-1843.2005.00663.x-i1

Abstract

The effect of lung volume on airway closure in severe asthma has not been extensively studied. Methods: Six intubated, mechanically ventilated patients (17 to 71 years of age) recovering from acute sever asthma were studied. The amplitude of cardiogenic airway pressure oscillations during external airflow interruption at different lung volumes was used to explore lung volume dependence of airway closure. ... Conclusions: The data suggest that widespread airway closure frequently does not occur when lung volume decreases from end-inspiration to FRC in patients recovering from acute sever asthma, possibly because an increase in FRC opposes the development of airway closure.

Original language	English
Pages	A28-A28
DOIs	https://doi.org/10.1111/j.1440-1843.2005.00663.x-i1
Publication status	Published - 2005
Event	TSANZ ASM 2005: Thoracic Society of Australia and New Zealand Annual Scientific Meeting - Perth, Australia Duration: 18 Mar 2005 → 23 Mar 2005

Conference

Conference	TSANZ ASM 2005: Thoracic Society of Australia and New Zealand Annual Scientific Meeting
City	Perth, Australia
Period	18/03/05 → 23/03/05

Keywords

Respiratory Diseases

Access to Document

10.1111/j.1440-1843.2005.00663.x-i1

https://hdl.handle.net/1959.11/10085

Handle.net

Persistent link

Cite this

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title = "Effects of lung volume on airway closure during recovery from acute severe asthma",

abstract = "The effect of lung volume on airway closure in severe asthma has not been extensively studied. Methods: Six intubated, mechanically ventilated patients (17 to 71 years of age) recovering from acute sever asthma were studied. The amplitude of cardiogenic airway pressure oscillations during external airflow interruption at different lung volumes was used to explore lung volume dependence of airway closure. ... Conclusions: The data suggest that widespread airway closure frequently does not occur when lung volume decreases from end-inspiration to FRC in patients recovering from acute sever asthma, possibly because an increase in FRC opposes the development of airway closure.",

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author = "\{van der Touw\}, Tom",

year = "2005",

doi = "10.1111/j.1440-1843.2005.00663.x-i1",

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note = "TSANZ ASM 2005: Thoracic Society of Australia and New Zealand Annual Scientific Meeting ; Conference date: 18-03-2005 Through 23-03-2005",

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AU - van der Touw, Tom

PY - 2005

Y1 - 2005

N2 - The effect of lung volume on airway closure in severe asthma has not been extensively studied. Methods: Six intubated, mechanically ventilated patients (17 to 71 years of age) recovering from acute sever asthma were studied. The amplitude of cardiogenic airway pressure oscillations during external airflow interruption at different lung volumes was used to explore lung volume dependence of airway closure. ... Conclusions: The data suggest that widespread airway closure frequently does not occur when lung volume decreases from end-inspiration to FRC in patients recovering from acute sever asthma, possibly because an increase in FRC opposes the development of airway closure.

AB - The effect of lung volume on airway closure in severe asthma has not been extensively studied. Methods: Six intubated, mechanically ventilated patients (17 to 71 years of age) recovering from acute sever asthma were studied. The amplitude of cardiogenic airway pressure oscillations during external airflow interruption at different lung volumes was used to explore lung volume dependence of airway closure. ... Conclusions: The data suggest that widespread airway closure frequently does not occur when lung volume decreases from end-inspiration to FRC in patients recovering from acute sever asthma, possibly because an increase in FRC opposes the development of airway closure.

KW - Respiratory Diseases

U2 - 10.1111/j.1440-1843.2005.00663.x-i1

DO - 10.1111/j.1440-1843.2005.00663.x-i1

M3 - Abstract

SP - A28-A28

T2 - TSANZ ASM 2005: Thoracic Society of Australia and New Zealand Annual Scientific Meeting

Y2 - 18 March 2005 through 23 March 2005

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