Assessing the value of metafounders for genomic prediction in Australian Simmental beef cattle

D J A Santos; N K Connors; P M Gurman; M H Ferdosi; S P Miller; A A Swan

Assessing the value of metafounders for genomic prediction in Australian Simmental beef cattle

D J A Santos
, N K Connors
, P M Gurman
, M H Ferdosi
, S P Miller
, A A Swan

Animal Genetics and Breeding Unit

Research output: Contribution to journal › Conference article › peer-review

Abstract

The “metafounders” framework is used to augment relationship matrixes to accommodate genetic structure in founder populations, and can be estimated from genotypes, making it useful to align pedigree and genomic relationships in single-step genomic analyses. This paper aimed to assess the value of metafounders in the genomic evaluation of beef traits in Australian Simmental cattle, and in particular the possibility of collapsing genetic groupings based on metafounder similarity. Estimated breeding values from metafounder models with different groupings had similar predictive ability across 12 beef traits, while models with higher weighting on genomic relative to pedigree information tended to perform better.

Original language	English
Pages (from-to)	158-161
Journal	Proceedings of the Association for the Advancement of Animal Breeding and Genetics
Volume	25
Publication status	Published - 26 Jul 2023
Event	AAABG 2023: 25th Conference of the Association for the Advancement of Animal Breeding and Genetics - The University Club of Western Australia, Perth, Australia Duration: 26 Jul 2023 → 28 Jul 2023

Access to Document

Handle.net

Persistent link

Cite this

@article{65df9affe3614814a9e6f22cc4dfc315,

title = "Assessing the value of metafounders for genomic prediction in Australian Simmental beef cattle",

abstract = "The {\textquotedblleft}metafounders{\textquotedblright} framework is used to augment relationship matrixes to accommodate genetic structure in founder populations, and can be estimated from genotypes, making it useful to align pedigree and genomic relationships in single-step genomic analyses. This paper aimed to assess the value of metafounders in the genomic evaluation of beef traits in Australian Simmental cattle, and in particular the possibility of collapsing genetic groupings based on metafounder similarity. Estimated breeding values from metafounder models with different groupings had similar predictive ability across 12 beef traits, while models with higher weighting on genomic relative to pedigree information tended to perform better.",

author = "Santos, \{D J A\} and Connors, \{N K\} and Gurman, \{P M\} and Ferdosi, \{M H\} and Miller, \{S P\} and Swan, \{A A\}",

year = "2023",

month = jul,

day = "26",

language = "English",

volume = "25",

pages = "158--161",

journal = "Proceedings of the Association for the Advancement of Animal Breeding and Genetics",

issn = "1328-3227",

publisher = "Association for the Advancement of Animal Breeding and Genetics (AAABG)",

note = "AAABG 2023: 25th Conference of the Association for the Advancement of Animal Breeding and Genetics ; Conference date: 26-07-2023 Through 28-07-2023",

}

TY - JOUR

T1 - Assessing the value of metafounders for genomic prediction in Australian Simmental beef cattle

AU - Santos, D J A

AU - Connors, N K

AU - Gurman, P M

AU - Ferdosi, M H

AU - Miller, S P

AU - Swan, A A

PY - 2023/7/26

Y1 - 2023/7/26

N2 - The “metafounders” framework is used to augment relationship matrixes to accommodate genetic structure in founder populations, and can be estimated from genotypes, making it useful to align pedigree and genomic relationships in single-step genomic analyses. This paper aimed to assess the value of metafounders in the genomic evaluation of beef traits in Australian Simmental cattle, and in particular the possibility of collapsing genetic groupings based on metafounder similarity. Estimated breeding values from metafounder models with different groupings had similar predictive ability across 12 beef traits, while models with higher weighting on genomic relative to pedigree information tended to perform better.

AB - The “metafounders” framework is used to augment relationship matrixes to accommodate genetic structure in founder populations, and can be estimated from genotypes, making it useful to align pedigree and genomic relationships in single-step genomic analyses. This paper aimed to assess the value of metafounders in the genomic evaluation of beef traits in Australian Simmental cattle, and in particular the possibility of collapsing genetic groupings based on metafounder similarity. Estimated breeding values from metafounder models with different groupings had similar predictive ability across 12 beef traits, while models with higher weighting on genomic relative to pedigree information tended to perform better.

UR - http://www.aaabg.org/aaabghome/proceedings25.php

M3 - Conference article

SN - 1328-3227

VL - 25

SP - 158

EP - 161

JO - Proceedings of the Association for the Advancement of Animal Breeding and Genetics

JF - Proceedings of the Association for the Advancement of Animal Breeding and Genetics

T2 - AAABG 2023: 25th Conference of the Association for the Advancement of Animal Breeding and Genetics

Y2 - 26 July 2023 through 28 July 2023

ER -

Assessing the value of metafounders for genomic prediction in Australian Simmental beef cattle

Abstract

Access to Document

Handle.net

Fingerprint

Cite this