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A Comprehensive Insight Towards Pharmaceutical Aspects of Graphene Nanosheets

  • Fatemeh Emadi
  • , Arash Emadi
  • , Ahmad Gholami

Research output: Contribution to journalArticlepeer-review

25 Citations (Scopus)

Abstract

Graphene Derivatives (GDs) have captured the interest and imagination of pharmaceutical scientists. This review exclusively provides pharmacokinetics and pharmacodynamics information with a particular focus on biopharmaceuticals. GDs can be used as multipurpose pharmaceutical delivery systems due to their ultra-high surface area, flexibility, and fast mobility of charge carriers. Improved effects, targeted delivery to tissues, controlled release profiles, visualization of biodistribution and clearance, and overcoming drug resistance are examples of the benefits of GDs. This review focuses on the application of GDs for the delivery of biopharmaceuticals. Also, the pharmacokinetic properties and the advantage of using GDs in pharmaceutics will be reviewed to achieve a comprehensive understanding about the GDs in pharmaceutical sciences.

Original languageEnglish
Pages (from-to)1016-1027
JournalCurrent Pharmaceutical Biotechnology
Volume21
Issue number11
DOIs
Publication statusPublished - 21 Sept 2020

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